There are 15 large scale industries and 1904 small scale industries in the district and 203 other factories and workshops. There are 97 cotton ginning mills and 101 oil mills.
The major industries are:
The Singareni Collieries Co. Ltd, Bellampally
Coal Chemical Complex, Ramakrishnapur,
The Sirpur Paper Mills Ltd., Kagaznagar
Orient Cement Factory, Devapur
The Mancherial Cement Co. Ltd, Mancherial
Adilabad Cotton & Oil Mills, Adilabad
Uma Ginning Factory, Adilabad
Quality Spinning Mills, Bhainsa
The Adilabad Cotton Growers Coop.
The Nataraj Spinning and Weaving mill, Nirma
Annapurna Cement Ltd., Samela, Asifabad.
The SirSilk Ltd., Kagaznagar [Now Defunct]
Annapurna Cement Ltd., Samela, Asifabad.
Penganga Oils Ltd., Adilabad
Sri Sai Venkat Oil Industries,Adilabad